Independent clinical-genomics software

Support VarSage

VarSage is maintained as an independent project for rare-disease variant prioritization, carrier screening, trio review, and auditable research reports.

Donations help cover reference-data maintenance, infrastructure, testing time, documentation, and continued development of careful decision-support workflows.

Donate now Review the knowledge base

What your support funds

1Reliable reference workflows Curating, checking, and documenting HPO, transcript, annotation, GWAS, and gene-phenotype resources used by the app.
2Safer clinical-review UX Keeping evidence categories clear, preserving provenance, and improving reports without turning software output into a diagnosis.
3Maintenance and testing Regression tests, example cases, browser checks, and packaging work that keep local and deployed runs aligned.

Local-firstCore analysis runs on the host machine, with external services used only when configured.

Evidence separatedPhenotype, inheritance, population, clinical assertion, ACMG-oriented, and GWAS context remain distinct.

Expert reviewOutputs are built for trained reviewers who need traceable candidate evidence and clear caveats.

Thank you for supporting careful variant interpretation tools. Donations support maintenance and development. They do not influence analysis behavior, ranking rules, evidence weighting, or report conclusions.